Entries by NEC Labs America

T-Cell Receptor-Peptide Interaction Prediction with Physical Model Augmented Pseudo-Labeling

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Predicting the interactions between T-cell receptors (TCRs) and peptides is crucial for the development of personalized medicine and targeted vaccine in immunotherapy. Current datasets for training deep learning models of this purpose remain constrained without diverse TCRs and peptides. To combat the data scarcity issue presented in the current datasets, we propose to extend the training dataset by physical modeling of TCR-peptide pairs. Specifically, we compute the docking energies between auxiliary unknown TCR-peptide pairs as surrogate training labels. Then, we use these extended example-label pairs to train our model in a supervised fashion. Finally, we find that the AUC score for the prediction of the model can be further improved by pseudo-labeling of such unknown TCR-peptide pairs (by a trained teacher model), and re-training the model with those pseudo-labeled TCR-peptide pairs. Our proposed method that trains the deep neural network with physical modeling and data-augmented pseudo-labeling improves over baselines in the available two datasets. We also introduce a new dataset that contains over 80,000 unknown TCR-peptide pairs with docking energy scores.

Template Matching Method with Distributed Acoustic Sensing Data and Simulation Data

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We propose a new method to detect acoustic signals by matching distributed acoustic sensing data with simulation. In the simulation of the dynamic strain on an optical fiber, the optical fiber layouts and the gauge length are properly incorporated. We apply the proposed method to the acoustic-source localization and demonstrate the method localizes the source accurately even under the layouts which include the straight optical fiber for the sensing points with the large gauge-length settings.

Simultaneous Fiber Sensing and Communications

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We review recent advances aimed at increasing the reach of distributed fiber optic sensing with simultaneous data transmission. We review two methods based on measurement of accumulated phase on telecom signals, and chirp-pulsed DAS with inline amplification and frequency diversity.

Mosaic: Leveraging Diverse Reflector Geometries for Omnidirectional Around-Corner Automotive Radar

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A large number of traffic collisions occur as a result of obstructed sight lines, such that even an advanced driver assistance system would be unable to prevent the crash. Recent work has proposed the use of around-the-corner radar systems to detect vehicles, pedestrians, and other road users in these occluded regions. Through comprehensive measurement, we show that these existing techniques cannot sense occluded moving objects in many important real-world scenarios. To solve this problem of limited coverage, we leverage multiple, curved reflectors to provide comprehensive coverage over the most important locations near an intersection. In scenarios where curved reflectors are insufficient, we evaluate the relative benefits of using additional flat planar surfaces. Using these techniques, we more than double the probability of detecting a vehicle near the intersection in three real urban locations and enable NLoS radar sensing using an entirely new class of reflectors.

StyleT2I: Towards Compositional and High-Fidelity Text-to-Image Synthesis

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Although progress has been made for text-to-image synthesis, previous methods fall short of generalizing to unseen or underrepresented attribute compositions in the input text. Lacking compositionality could have severe implications for robustness and fairness, e.g., inability to synthesize the face images of underrepresented demographic groups. In this paper, we introduce a new framework, StyleT2I, to improve the compositionality of text-to-image synthesis. Specifically, we propose a CLIP-guided Contrastive Loss to better distinguish different compositions among different sentences. To further improve the compositionality, we design a novel Semantic Matching Loss and a Spatial Constraint to identify attributes’ latent directions for intended spatial region manipulations, leading to better disentangled latent representations of attributes. Based on the identified latent directions of attributes, we propose Compositional Attribute Adjustment to adjust the latent code, resulting in better compositionality of image synthesis. In addition, we leverage the l2 -norm regularization of identified latent directions (norm penalty) to strike a nice balance between image-text alignment and image fidelity. In the experiments, we devise a new dataset split and an evaluation metric to evaluate the compositionality of text-to-image synthesis models. The results show that StyleT2I outperforms previous approaches in terms of the consistency between the input text and synthesized images and achieves higher fidelity

Chimera: Context-Aware Splittable Deep Multitasking Models for Edge Intelligence

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Design of multitasking deep learning models has mostly focused on improving the accuracy of the constituent tasks, but the challenges of efficiently deploying such models in a device-edge collaborative setup (that is common in 5G deployments) has not been investigated. Towards this end, in this paper, we propose an approach called Chimera 1 for training (done Offline) and deployment (done Online) of multitasking deep learning models that are splittable across the device and edge. In the offline phase, we train our multi-tasking setup such that features from a pre-trained model for one of the tasks (called the Primary task) are extracted and task-specific sub-models are trained to generate the other (Secondary) tasks’ outputs through a knowledge distillation like training strategy to mimic the outputs of pre-trained models for the tasks. The task-specific sub-models are designed to be significantly lightweight than the original pre-trained models for the Secondary tasks. Once the sub-models are trained, during deployment, for given deployment context, characterized by the configurations, we search for the optimal (in terms of both model performance and cost) deployment strategy for the generated multitasking model, through finding one or multiple suitable layer(s) for splitting the model, so that inference workloads are distributed between the device and the edge server and the inference is done in a collaborative manner. Extensive experiments on benchmark computer vision tasks demonstrate that Chimera generates splittable multitasking models that are at least ~ 3 x parameter efficient than the existing such models, and the end-to-end device-edge collaborative inference becomes ~ 1.35 x faster with our choice of context-aware splitting decisions.

Weakly But Deeply Supervised Occlusion-Reasoned Parametric Road Layouts

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We propose an end-to-end network that takes a single perspective RGB image of a complex road scene as input, to produce occlusion-reasoned layouts in perspective space as well as a parametric bird’s-eye-view (BEV) space. In contrast to prior works that require dense supervision such as semantic labels in perspective view, our method only requires human annotations for parametric attributes that are cheaper and less ambiguous to obtain. To solve this challenging task, our design is comprised of modules that incorporate inductive biases to learn occlusion-reasoning, geometric transformation and semantic abstraction, where each module may be supervised by appropriately transforming the parametric annotations. We demonstrate how our design choices and proposed deep supervision help achieve meaningful representations and accurate predictions. We validate our approach on two public datasets, KITTI and NuScenes, to achieve state-of-the-art results with considerably less human supervision.