Model-Based Autoencoders for Imputing Discrete single-cell RNA-seq Data

/in /by

Deep neural networks have been widely applied for missing data imputation. However, most existing studies have been focused on imputing continuous data, while discrete data imputation is under-explored. Discrete data is common in real world, especially in research areas of bioinformatics, genetics, and biochemistry. In particular, large amounts of recent genomic data are discrete count data generated from single-cell RNA sequencing (scRNA-seq) technology. Most scRNA-seq studies produce a discrete matrix with prevailing ‘false’ zero count observations (missing values). To make downstream analyses more effective, imputation, which recovers the missing values, is often conducted as the first step in pre-processing scRNA-seq data. In this paper, we propose a novel Zero-Inflated Negative Binomial (ZINB) model-based autoencoder for imputing discrete scRNA-seq data. The novelties of our method are twofold. First, in addition to optimizing the ZINB likelihood, we propose to explicitly model the dropout events that cause missing values by using the Gumbel-Softmax distribution. Second, the zero-inflated reconstruction is further optimized with respect to the raw count matrix. Extensive experiments on simulation datasets demonstrate that the zero-inflated reconstruction significantly improves imputation accuracy. Real data experiments show that the proposed imputation can enhance separating different cell types and improve the accuracy of differential expression analysis.

Read more

Anti-spoofing Face Recognition Using Infrared Structure Light

/in /by

We demonstrate an anti-spoofing face recognition system that is able to differentiate real human face with 3D printed materials. Face images captured in infrared structure light are analyzed for surface materials and spatial structure.

Read more

Tripping Through Time: Efficient Localization of Activities in Videos

/in /by

Localizing moments in untrimmed videos via language queries is a new and interesting task that requires the ability to accurately ground language into video. Previous works have approached this task by processing the entire video, often more than once, to localize relevant activities. In the real world applications of this approach, such as video surveillance, efficiency is a key system requirement. In this paper, we present TripNet, an end-to-end system that uses a gated attention architecture to model fine-grained textual and visual representations in order to align text and video content. Furthermore, TripNet uses reinforcement learning to efficiently localize relevant activity clips in long videos, by learning how to intelligently skip around the video. It extracts visual features for few frames to perform activity classification. In our evaluation over Charades-STA [14], ActivityNet Captions [26] and the TACoS dataset [36], we find that TripNet achieves high accuracy and saves processing time by only looking at 32-41% of the entire video.

Read more

Adaptation Across Extreme Variations using Unlabeled Bridges

/in /by

We tackle an unsupervised domain adaptation problem for which the domain discrepancy between labeled source and unlabeled target domains is large, due to many factors of inter- and intra-domain variation. While deep domain adaptation methods have been realized by reducing the domain discrepancy, these are difficult to apply when domains are significantly different. We propose to decompose domain discrepancy into multiple but smaller, and thus easier to minimize, discrepancies by introducing unlabeled bridging domains that connect the source and target domains. We realize our proposed approach through an extension of the domain adversarial neural network with multiple discriminators, each of which accounts for reducing discrepancies between unlabeled (bridge, target) domains and a mix of all precedent domains including source. We validate the effectiveness of our method on several adaptation tasks including object recognition and semantic segmentation.

Read more

Pseudo RGB-D for Self-Improving Monocular SLAM and Depth Prediction

/in /by

Classical monocular Simultaneous Localization And Mapping (SLAM) and the recently emerging convolutional neural networks (CNNs) for monocular depth prediction represent two largely disjoint approaches towards building a 3D map of the surrounding environment. In this paper, we demonstrate that the coupling of these two by leveraging the strengths of each mitigates the other’s shortcomings. Specifically, we propose a joint narrow and wide baseline based self-improving framework, where on the one hand the CNN-predicted depth is leveraged to perform $ extit(Unknown sysvar: (pseudo))$ RGB-D feature-based SLAM, leading to better accuracy and robustness than the monocular RGB SLAM baseline. On the other hand, the bundle-adjusted 3D scene structures and camera poses from the more principled geometric SLAM are injected back into the depth network through novel wide baseline losses proposed for improving the depth prediction network, which then continues to contribute towards better pose and 3D structure estimation in the next iteration. We emphasize that our framework only requires $ extit(Unknown sysvar: ( unlabeled monocular))$ videos in both training and inference stages, and yet is able to outperform state-of-the-art self-supervised $ extit(Unknown sysvar: (monocular))$ and $ extit(Unknown sysvar: (stereo))$ depth prediction networks (e.g, Monodepth2) and feature based monocular SLAM system (i.e, ORB-SLAM). Extensive experiments on KITTI and TUM RGB-D datasets verify the superiority of our self-improving geometry-CNN framework.

Read more

Domain Adaptive Semantic Segmentation using Weak Labels

/in /by

We propose a novel framework for domain adaptation in semantic segmentation with image-level weak labels in the target domain. The weak labels may be obtained based on a model prediction for unsupervised domain adaptation (UDA), or from a human oracle in a new weakly-supervised domain adaptation (WDA) paradigm for semantic segmentation. Using weak labels is both practical and useful, since (i) collecting image-level target annotations is comparably cheap in WDA and incurs no cost in UDA, and (ii) it opens the opportunity for category-wise domain alignment. Our framework uses weak labels to enable the interplay between feature alignment and pseudo-labeling, improving both in the process of domain adaptation. Specifically, we develop a weak-label classification module to enforce the network to attend to certain categories, and then use such training signals to guide the proposed category-wise alignment method. In experiments, we show considerable improvements with respect to the existing state-of-the-arts in UDA and present a new benchmark in the WDA setting.

Read more

Image Stitching and Rectification for Hand-Held Cameras

/in /by

In this paper, we derive a new differential homography that can account for the scanline-varying camera poses in Rolling Shutter (RS) cameras, and demonstrate its application to carry out RS-aware image stitching and rectification at one stroke. Despite the high complexity of RS geometry, we focus in this paper on a special yet common input — two consecutive frames from a video stream, wherein the inter-frame motion is restricted from being arbitrarily large. This allows us to adopt simpler differential motion model, leading to a straightforward and practical minimal solver. To deal with non-planar scene and camera parallax in stitching, we further propose an RS-aware spatially-varying homogarphy field in the principle of As-Projective-As-Possible (APAP). We show superior performance over state-of-the-art methods both in RS image stitching and rectification, especially for images captured by hand-held shaking cameras.

Read more

Improving Face Recognition by Clustering Unlabeled Faces in the Wild

/in /by

While deep face recognition has benefited significantly from large-scale labeled data, current research is focused on leveraging unlabeled data to further boost performance, reducing the cost of human annotation. Prior work has mostly been in controlled settings, where the labeled and unlabeled data sets have no overlapping identities by construction. This is not realistic in large-scale face recognition, where one must contend with such overlaps, the frequency of which increases with the volume of data. Ignoring identity overlap leads to significant labeling noise, as data from the same identity is split into multiple clusters. To address this, we propose a novel identity separation method based on extreme value theory. It is formulated as an out-of-distribution detection algorithm, and greatly reduces the problems caused by overlapping-identity label noise. Considering cluster assignments as pseudo-labels, we must also overcome the labeling noise from clustering errors. We propose a modulation of the cosine loss, where the modulation weights correspond to an estimate of clustering uncertainty. Extensive experiments on both controlled and real settings demonstrate our method’s consistent improvements over supervised baselines, e.g., 11.6% improvement on IJB-A verification.

Read more

Learning Monocular Visual Odometry via Self-Supervised Long-Term Modeling

/in /by

Monocular visual odometry (VO) suffers severely from error accumulation during frame-to-frame pose estimation. In this paper, we present a self-supervised learning method for VO with special consideration for consistency over longer sequences. To this end, we model the long-term dependency in pose prediction using a pose network that features a two-layer convolutional LSTM module. We train the networks with purely self-supervised losses, including a cycle consistency loss that mimics the loop closure module in geometric VO. Inspired by prior geometric systems, we allow the networks to see beyond a small temporal window during training, through a novel a loss that incorporates temporally distant ( g $O(100)$) frames. Given GPU memory constraints, we propose a stage-wise training mechanism, where the first stage operates in a local time window and the second stage refines the poses with a “global” loss given the first stage features. We demonstrate competitive results on several standard VO datasets, including KITTI and TUM RGB-D.

Read more

Learning to Optimize Domain Specific Normalization for Domain Generalization

/in /by

We propose a simple but effective multi-source domain generalization technique based on deep neural networks by incorporating optimized normalization layers that are specific to individual domains. Our approach employs multiple normalization methods while learning separate affine parameters per domain. For each domain, the activations are normalized by a weighted average of multiple normalization statistics. The normalization statistics are kept track of separately for each normalization type if necessary. Specifically, we employ batch and instance normalizations in our implementation to identify the best combination of these two normalization methods in each domain. The optimized normalization layers are effective to enhance the generalizability of the learned model. We demonstrate the state-of-the-art accuracy of our algorithm in the standard domain generalization benchmarks, as well as viability to further tasks such as multi-source domain adaptation and domain generalization in the presence of label noise.

Read more